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Inflammatory Biomarker Associated with Mitochondrial Decline Further Linked to Frailty

Researchers at the Johns Hopkins University School of Medicine have developed a mouse model that successfully mimics the development of frailty as mammals — likely including people — get older.

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New Findings Show Mitochondrial DNA Fragments in Blood as Important Biomarkers for Aging and Inflammation

In an eight-year study of more than 600 community-dwelling older adults, Johns Hopkins Medicine researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic ...

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New Studies Suggest Social Isolation Is a Risk Factor for Dementia in Older Adults, Point to Ways to Reduce Risk

In two studies using nationally representative data from the National Health and Aging Trends Study gathered on thousands of Americans, researchers from the Johns Hopkins University School of Medicine and Bloomberg School of Public Health ...

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Research Focuses on Improving Care for People with Dementia

Adults with dementia are sometimes thought to be homogenous and presumed to use a lot of health care services, especially later in life, says geriatrician Stephanie Nothelle. But two recent studies Nothelle directed suggest that’s not the case.

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Johns Hopkins Research Suggests Ways to Improve the Medicare Annual Wellness Visit

A new study from Johns Hopkins researchers offers caution about the limitations of the Medicare Annual Wellness Visit, finding that up to 25% of older adults at risk for falls still were prescribed a medication that is considered high risk for that condition.

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Family Caregivers Share Both Positive And Challenging Experiences In New Study

An old adage goes something like this: “Growing old is not for the faint of heart.” Perhaps there’s something else about the aging human condition at parity with this wisdom: caregiving is both challenging and rewarding.

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Understanding Patient Preferences for Deprescribing Medications

Geriatricians routinely see older adults who are prescribed an overload of medicines that may not benefit them or be aligned with their goals —and that often cause harm including falls, cognitive impairment, hospitalization and death. ...